Acetyl Hexapeptide-8 (Argireline): softening the look of expression lines
Acetyl hexapeptide-8, widely known by the trade name Argireline, is a six-amino-acid peptide used in skincare to soften the look of expression lines, such as those around the eyes and on the forehead.
What it is
Acetyl hexapeptide-8 is a short peptide modelled on a fragment of a protein involved in the signals that make facial muscles contract. It is one of the most widely used and studied cosmetic peptides.
What the research looks at
Expression lines form where the skin folds over and over with movement. Research on acetyl hexapeptide-8 has looked at how it moderates the signalling behind those repeated contractions at the skin's surface level. In cosmetic use, it is chosen to help soften the look of expression lines with consistent use.
Why it is in Vellura
Acetyl hexapeptide-8 addresses a different aspect of ageing skin from the firming and calming peptides in the VX-8™ network: lines caused by movement rather than by loss of firmness. It is dosed in the ranges its suppliers recommend and published studies use.
Good to know
- It does not freeze expression. It is a topical cosmetic ingredient, not an injectable.
- Best applied where expression lines form: around the eyes, forehead and mouth.
- Pairs well with firming peptides and hydrators.
Questions
Is Argireline the same as Botox?
No. Injectable treatments work very differently. Acetyl hexapeptide-8 is a cosmetic ingredient that helps soften the look of expression lines on the skin's surface.
How long before I see a difference?
Cosmetic peptides work gradually. Give any product several weeks of consistent use.
Read next: Matrixyl vs Argireline: which peptide do you need?
Longevity Skincare, Explained · Explore the VX-8™ platform · Glossary · Back to the Ingredient Library · Join the Founding Edition list
Cosmetic information only. Vellura products are cosmetics and are not intended to diagnose, treat or prevent any condition.